Cdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase.
Cdc7p-Dbf4p is a conserved protein kinase required for the initiation of DNA replication. The Dbf4p regulatory subunit binds Cdc7p and is essential for Cdc7p kinase activation, however, the N-terminal third of Dbf4p is dispensable for its essential replication activities. Here, we define a short N-t...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science (PLoS)
2009-05-01
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| Serie: | PLoS Genetics |
| Accesso online: | http://europepmc.org/articles/PMC2682205?pdf=render |
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