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Neuronal Subtype and Satellite Cell Tropism Are Determinants of Varicella-Zoster Virus Virulence in Human Dorsal Root Ganglia Xenografts In Vivo.

Varicella zoster virus (VZV), a human alphaherpesvirus, causes varicella during primary infection. VZV reactivation from neuronal latency may cause herpes zoster, post herpetic neuralgia (PHN) and other neurologic syndromes. To investigate VZV neuropathogenesis, we developed a model using human dors...

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Détails bibliographiques
Auteurs principaux: Leigh Zerboni, Ann Arvin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2015-06-01
Collection:PLoS Pathogens
Accès en ligne:http://europepmc.org/articles/PMC4474629?pdf=render
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