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Post-translational polymodification of β1-tubulin regulates motor protein localization in platelet production and function

In specialized cells, the expression of specific tubulin isoforms and their subsequent post-translational modifications drive and coordinate unique morphologies and behaviors. The mechanisms by which β1-tubulin, the platelet and megakaryocyte (MK) lineage restricted tubulin isoform, drives platelet...

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Autors principals: Abdullah O. Khan, Alexandre Slater, Annabel Maclachlan, Phillip L.R. Nicolson, Jeremy A. Pike, Jasmeet S. Reyat, Jack Yule, Rachel Stapley, Julie Rayes, Steven G. Thomas, Neil V. Morgan
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2020-12-01
Col·lecció:Haematologica
Accés en línia:https://haematologica.org/article/view/10119
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