Cost-effectiveness of intradiscal injection with condoliase versus microendoscopic discectomy for lumbar disc herniation: a retrospective multicenter study

Abstract Intradiscal condoliase injection has been described as a safe treatment with relatively favorable results. In Japan, the direct medical cost of intradiscal condoliase injection is significantly lower than that of microendoscopic discectomy (MED). The objective of this study was to assess th...

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Autori principali:	Takuya Takahashi, Hiroyuki Sato, Yohei Takahashi, Kota Watanabe, Tomohiro Banno, Kyohei Sakaki, Yoshiyasu Arai, Yuichi Takano, Yawara Eguchi, Yuki Taniguchi, Satoshi Maki, Yasuchika Aoki, Toshitaka Yoshii, Hiroshi Yamada, Takashi Kaito, Yutaka Hiraizumi, Masatune Yamagata, Masaya Nakamura, Naobumi Hosogane, Akihiro Hirakawa, Seiji Ohtori, Takashi Hirai
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-12-01
Serie:	Scientific Reports
Soggetti:	Condoliase Microendoscopic discectomy Lumbar disc herniation Cost-effectiveness
Accesso online:	https://doi.org/10.1038/s41598-025-27802-3
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