Effect of 3% saline and furosemide on biomarkers of kidney injury and renal tubular function and GFR in healthy subjects – a randomized controlled trial

Abstract Background Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop-diuretic furosemide. Methods The study was designed as a randomized, p...

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Үндсэн зохиолчид:	F. H. Mose, A. N. Jörgensen, M. H. Vrist, N. P. Ekelöf, E. B. Pedersen, J. N. Bech
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2019-06-01
Цуврал:	BMC Nephrology
Нөхцлүүд:	Hypertonic saline 3% saline Hyperchloremic acidosis NGAL KIM-1 Fractional excretion of sodium
Онлайн хандалт:	http://link.springer.com/article/10.1186/s12882-019-1342-x
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!