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Oxidative stress and hepcidin expression in pediatric sickle cell anemia with iron overload

Background: Blood transfusion (BT) is essential in treating sickle cell disease (SCD); however, it leads to iron overload (IO) and oxidative stress. We studied the relationship between oxidative stress, iron status parameters, hepcidin mRNA gene expression, and IO in SCD patients. Methods: We classi...

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Hlavní autoři: Eman A. Elbostany, Eman A. Elghoroury, Eman H. Thabet, Alaa A. Rashad, Enas A. Rasheed, Gamila S.M. El-Saeed, Dalia A. Abdelhalim, Safa N. Abdelfattah, Iman I. Salama, Niveen Salama
Médium: Artigo
Jazyk:Inglês
Vydáno: Wolters Kluwer Medknow Publications 2023-07-01
Edice:Hematology/Oncology and Stem Cell Therapy
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On-line přístup:https://journals.lww.com/10.1016/j.hemonc.2021.11.003
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