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Computational inference of chemokine-mediated roles for the vagus nerve in modulating intra- and inter-tissue inflammation

Introduction: The vagus nerve innervates multiple organs, but its role in regulating cross-tissue spread of inflammation is as yet unclear. We hypothesized that the vagus nerve may regulate cross-tissue inflammation via modulation of the putatively neurally regulated chemokine IP-10/CXCL10.Methods:...

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Principais autores: Ashti M. Shah, Ruben Zamora, Derek Barclay, Jinling Yin, Fayten El-Dehaibi, Meghan Addorisio, Tea Tsaava, Aisling Tynan, Kevin Tracey, Sangeeta S. Chavan, Yoram Vodovotz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-02-01
coleção:Frontiers in Systems Biology
Assuntos:
vagus nerve
vagotomy
inflammation
chemokines
systems biology
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fsysb.2024.1266279/full
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