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Pre-activated lyophilized platelets show non-inferior hemostatic effect compared with fresh platelets in rabbits with traumatic bleeding and shock

Background A high activation level is a normal characteristic of lyophilized platelets (LPs); however, the effects of this activation level on the efficacy and safety of LPs after transfusion are debated.Objectives We aimed to test the efficacy and safety of pre-activated LPs (PLPs) in rabbits with...

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Principais autores: Chenglin Dai, Wenqiong Du, Na Kang, Haoyang Yang, Ting Tang, Yijun Jia, Can Chen, Zhaowen Zong
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2025-12-01
Serier:Platelets
Fag:
Bleeding control
hemorrhagic shock
hemostatic effect
lyophilized platelets
pre-activation
Online adgang:https://www.tandfonline.com/doi/10.1080/09537104.2025.2542767
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