Colistin-degrading proteases confer collective resistance to microbial communities during polymicrobial infections

Abstract Background The increasing prevalence of resistance against the last-resort antibiotic colistin is a significant threat to global public health. Here, we discovered a novel colistin resistance mechanism via enzymatic inactivation of the drug and proposed its clinical importance in microbial...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Do-Hoon Lee, Ju-Hee Cha, Dae-Wi Kim, Kihyun Lee, Yong-Seok Kim, Hyo-Young Oh, You-Hee Cho, Chang-Jun Cha
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2022-08-01
Sarja:	Microbiome
Aiheet:	Colistin Antimicrobial resistance Colistin-degrading protease Collective resistance Polymicrobial infection Stenotrophomonas maltophilia
Linkit:	https://doi.org/10.1186/s40168-022-01315-x
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