TDG is a novel tumor suppressor of liver malignancies
In a recent publication, we demonstrated that conditional deletion of the gene encoding thymine DNA glycosylase (TDG) leads to a late onset of hepatocellular carcinoma (HCC). TDG loss causes disruption in active DNA demethylation in the liver and dysregulation of the farnesoid X receptor and small h...
Guardado en:
| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Taylor & Francis Group
2020-07-01
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| Colección: | Molecular & Cellular Oncology |
| Materias: | |
| Acceso en línea: | http://dx.doi.org/10.1080/23723556.2020.1768819 |
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