TEM8 Tri-specific Killer Engager binds both tumor and tumor stroma to specifically engage natural killer cell anti-tumor activity

Background The tumor microenvironment contains stromal cells, including endothelial cells and fibroblasts, that aid tumor growth and impair immune cell function. Many solid tumors remain difficult to cure because of tumor-promoting stromal cells, but current therapies targeting tumor stromal cells a...

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Auteurs principaux:	Jeffrey S Miller, Behiye Kodal, Martin Felices, Peter Hinderlie, Michael F Kaminski, Laura Bendzick, Rachel Hopps, Marissa Kauffman, Yvette Soignier, Joshua T Walker, Todd R Lenvik, Melissa A Geller
Format:	Artigo
Langue:	Inglês
Publié:	BMJ Publishing Group 2022-09-01
Collection:	Journal for ImmunoTherapy of Cancer
Accès en ligne:	https://jitc.bmj.com/content/10/9/e004725.full
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