89Zr-labeled ImmunoPET targeting the cancer stem cell antigen CD133 using fully-human antibody constructs

Abstract Background Cancer stem cells play an important role in driving tumor growth and treatment resistance, which makes them a promising therapeutic target to prevent cancer recurrence. Emerging cancer stem cell-targeted therapies would benefit from companion diagnostic imaging probes to aid in p...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Kevin Wyszatko, Melissa Chassé, Nancy Janzen, Luis Rafael Silva, Luke Kwon, Teesha Komal, Manuela Ventura, Chitra Venugopal, Sheila K. Singh, John F. Valliant, Saman Sadeghi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	SpringerOpen 2024-03-01
Schriftenreihe:	EJNMMI Research
Schlagworte:	ImmunoPET Cancer Stem cells CD133 Zirconium-89 Antibody Antibody fragment
Online-Zugang:	https://doi.org/10.1186/s13550-024-01091-9
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!