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Metabolic Mechanisms of Hexavalent Chromium-Induced Splenic Immune Injury via Oxidative Stress and Ferroptosis Pathways in New Zealand Rabbits

<b>Background</b>: Hexavalent chromium (Cr(VI)) is a widespread environmental toxic heavy metal with strong oxidative properties; however, its immunotoxicity and metabolic mechanisms in rabbit spleen remain largely unclear. <b>Methods</b>: In this study, New Zealand rabbits were exposed to 0, 12.5,...

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Principais autores: Junzhao Yuan, Jiaqi Zhang, Jinxing Song, Lingling Liu, Hang Liu, Shuangxing Jin, Xiaoli Ren
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-06-01
Serier:Metabolites
Fag:
hexavalent chromium
rabbit spleen
immunotoxicity
redox metabolism
ferroptosis
Online adgang:https://www.mdpi.com/2218-1989/16/6/430
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