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High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos

Summary Recently, gene editing with transcription activator-like effector nucleases (TALENs) has been used in the life sciences. TALENs can be easily customized to recognize a specific DNA sequence and efficiently introduce double-strand breaks at the targeted genomic locus. Subsequent non-homologou...

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Hlavní autoři: Ken-ichi T. Suzuki, Yukiko Isoyama, Keiko Kashiwagi, Tetsushi Sakuma, Hiroshi Ochiai, Naoaki Sakamoto, Nobuaki Furuno, Akihiko Kashiwagi, Takashi Yamamoto
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists 2013-03-01
Edice:Biology Open
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On-line přístup:http://bio.biologists.org/content/2/5/448
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