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Lipid-associated PML structures assemble nuclear lipid droplets containing CCTα and Lipin1

PML proteins assemble into noncanonical lipid-associated PML structures (LAPS) on nuclear lipid droplets, which recruit CCTα and Lipin1 for the synthesis of phosphatidylcholine and triacylglycerol. Nuclear lipid droplets (nLDs) form on the inner nuclear membrane by a mechanism involving promyelocyti...

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Bibliografiske detaljer
Principais autores: Jonghwa Lee, Jayme Salsman, Jason Foster, Graham Dellaire, Neale D Ridgway
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2020-08-01
Serier:Life Science Alliance
Online adgang:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202000751
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