A novel method for predicting cell abundance based on single-cell RNA-seq data

Abstract Background It is important to understand the composition of cell type and its proportion in intact tissues, as changes in certain cell types are the underlying cause of disease in humans. Although compositions of cell type and ratios can be obtained by single-cell sequencing, single-cell se...

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Hlavní autoři:	Jiajie Peng, Lu Han, Xuequn Shang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-08-01
Edice:	BMC Bioinformatics
Témata:	Deconvolution Bioinformatics Cell abundance prediction Weighted least squares
On-line přístup:	https://doi.org/10.1186/s12859-021-04187-4
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