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Decreased FXR Agonism in the Bile Acid Pool Is Associated with Impaired FXR Signaling in a Pig Model of Pediatric NAFLD

The objective of this study was to investigate whether the impairment of farnesoid X receptor (FXR)-fibroblast growth factor 19 (FGF19) signaling in juvenile pigs with non-alcoholic fatty liver disease (NAFLD) is associated with changes in the composition of the enterohepatic bile acid pool. Eightee...

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Autors principals: Magdalena A. Maj, Douglas G. Burrin, Rodrigo Manjarín
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2023-12-01
Col·lecció:Biomedicines
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Accés en línia:https://www.mdpi.com/2227-9059/11/12/3303
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