Eschweilenol C and subfractions from Terminalia plants disrupt haemoglobin metabolism, inhibiting Plasmodium falciparum growth at rings and trophozoite stages

Abstract Background The rising prevalence of artemisinin-resistant malaria parasites in Africa underscores the urgent demand for new and effective therapeutic options. Historically, natural products have demonstrated significant anti-Plasmodium efficacy, indicating their potential as a source for ma...

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Главные авторы:	Mariscal Brice Tchatat Tali, Cedric Derick Jiatsa Mbouna, Aafreen Zehra, Steven Collins Njonte Wouamba, Guy Paulin Kemayou Mouthe, Aubin Youbi Kamche, Darline Dize, Simeon Fogue Kouam, Boniface Pone Kamdem, Jean Claude Tchouankeu, Feroz Khan, Fabrice Fekam Boyom
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2025-11-01
Серии:	Malaria Journal
Предметы:	Malaria Eschweilenol C Pharmacodynamics Molecular docking Pharmacokinetics
Online-ссылка:	https://doi.org/10.1186/s12936-025-05445-z
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