QR Code

Oxidative and Endoplasmic Reticulum Stress Represent Novel Therapeutic Targets for Choroideremia

Choroideremia (CHM) is a rare X-linked chorioretinal dystrophy, affecting the photoreceptors, retinal pigment epithelium (RPE) and choroid, with no approved therapy. CHM is caused by mutations in the <i>CHM</i> gene, which encodes the ubiquitously expressed Rab escort protein 1 (REP1). REP1 is invol...

Full description

Saved in:
Main Authors: Hajrah Sarkar, Manuela Lahne, Neelima Nair, Mariya Moosajee
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-08-01
Series:Antioxidants
Subjects:
choroideremia
oxidative stress
ER stress
neuroprotectants
zebrafish
patient fibroblasts
Online Access:https://www.mdpi.com/2076-3921/12/9/1694
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items