Overcoming hypoxia-induced functional suppression of NK cells
Background Natural killer (NK) cells are immune cells capable of killing virally infected cells and tumor cells without the need for antigen stimulation. Tumors, however, can create a suppressive microenvironment that decreases NK function. A feature of many tumors is hypoxia (low oxygen perfusion),...
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| Hlavní autoři: | , , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMJ Publishing Group
2020-05-01
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| Edice: | Journal for ImmunoTherapy of Cancer |
| On-line přístup: | https://jitc.bmj.com/content/8/1/e000246.full |
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