Evaluation of Epstein–Barr virus DNA methylation and load in saliva in the management of individuals at high risk of nasopharyngeal carcinoma

Abstract Background The current Epstein–Barr virus (EBV) antibody-based screening strategy for nasopharyngeal carcinoma (NPC) has been used for years. However, its low positive predictive value (PPV) often leads to unnecessary diagnostic procedures. Thus, further triage strategies are needed. Method...

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Prif Awduron:	Xiao-Hui Zheng, Ting Zhou, Xi-Zhao Li, Xiao-Jing Yang, Yu-Meng Zhang, Cao-Li Tang, Cheng-Tao Jiang, Pei-Fen Zhang, Ying Liao, Yong-Qiao He, Wen-Qiong Xue, Tong-Min Wang, Weimin Ye, Wei-Hua Jia
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2026-01-01
Cyfres:	Biomarker Research
Pynciau:	NPC screening Saliva EBV antibody EBV load DNA methylation
Mynediad Ar-lein:	https://doi.org/10.1186/s40364-026-00897-0
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