DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma.
Although osteosarcoma (OS) is a rare cancer, it is the most common primary malignant bone tumor in children and adolescents. BRCAness is a phenotypical trait in tumors with a defect in homologous recombination repair, resembling tumors with inactivation of BRCA1/2, rendering these tumors sensitive t...
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| Principais autores: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2021-11-01
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| coleção: | PLoS Computational Biology |
| Acesso em linha: | https://doi.org/10.1371/journal.pcbi.1009562 |
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