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Breast cancer metastasis: immune profiling of lymph nodes reveals exhaustion of effector T cells and immunosuppression

Sentinel lymph nodes are the first nodes draining the lymph from a breast and could reveal early changes in the host immune system upon dissemination of breast cancer cells. To investigate this, we performed single‐cell immune profiling of lymph nodes with and without metastatic cells. Whereas no si...

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Principais autores: Inga Hansine Rye, Kanutte Huse, Sarah E. Josefsson, Wanja Kildal, Håvard E. Danielsen, Ellen Schlichting, Øystein Garred, Margit L. Riis, OSBREAC, Ole Christian Lingjærde, June H. Myklebust, Hege G. Russnes
格式: Artigo
語言:Inglês
出版: Wiley 2022-01-01
叢編:Molecular Oncology
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在線閱讀:https://doi.org/10.1002/1878-0261.13047
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