Pre-Amplification of Cell-Free DNA: Balancing Amplification Errors with Enhanced Sensitivity

Circulating tumour DNA (ctDNA) is a promising biomarker for personalised oncology. However, its clinical utility is limited by detection sensitivity, particularly in early-stage disease. T-Oligo Primed Polymerase Chain Reaction (TOP-PCR) is a commercial amplification approach utilising an efficient...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Wei Yen Chan, Ashleigh Stewart, Russell J. Diefenbach, Elin S. Gray, Jenny H. Lee, Richard A. Scolyer, Georgina V. Long, Helen Rizos
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	MDPI AG 2025-06-01
Sarja:	Biomolecules
Aiheet:	circulating tumour DNA melanoma detection sensitivity
Linkit:	https://www.mdpi.com/2218-273X/15/6/883
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