Inhibition of Mef2a Enhances Neovascularization via Post-transcriptional Regulation of 14q32 MicroRNAs miR-329 and miR-494

Improving the efficacy of neovascularization is a promising strategy to restore perfusion of ischemic tissues in patients with peripheral arterial disease. The 14q32 microRNA cluster is highly involved in neovascularization. The Mef2a transcription factor has been shown to induce transcription of th...

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Bibliografiske detaljer

Principais autores:	Sabine M.J. Welten, Margreet R. de Vries, Erna A.B. Peters, Sudhir Agrawal, Paul H.A. Quax, A. Yaël Nossent
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2017-06-01
Serier:	Molecular Therapy: Nucleic Acids
Fag:	MEF2A miR-329 miR-494 14q32 neovascularization arteriogenesis angiogenesis posttranscriptional regulation RNA binding protein ischemia
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2162253117301415
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