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RNA length has a non-trivial effect in the stability of biomolecular condensates formed by RNA-binding proteins.

Biomolecular condensates formed via liquid-liquid phase separation (LLPS) play a crucial role in the spatiotemporal organization of the cell material. Nucleic acids can act as critical modulators in the stability of these protein condensates. To unveil the role of RNA length in regulating the stabil...

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Autori principali: Ignacio Sanchez-Burgos, Jorge R Espinosa, Jerelle A Joseph, Rosana Collepardo-Guevara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2022-02-01
Serie:PLoS Computational Biology
Accesso online:https://doi.org/10.1371/journal.pcbi.1009810
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