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Mapping carbon utilization pathways in Histoplasma capsulatum through 13C-metabolic flux analysis

ABSTRACT Histoplasma capsulatum is a human fungal pathogen that survives and proliferates within phagocytic immune cells. To sustain growth in the nutrient-limited phagosome environment, the pathogenic yeast scavenges available carbon sources, which must be metabolized through central carbon metabol...

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Bibliografische Detailangaben
Hauptverfasser: Adrian Heckart, Jean-Christophe Cocuron, Stephanie C. Ray, Gabriella F. Matheny, Chad A. Rappleye, Ana P. Alonso
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2025-10-01
Schriftenreihe:mSystems
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Online-Zugang:https://journals.asm.org/doi/10.1128/msystems.00569-25
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