1,25-dihydroxyvitamin D3 conditioned CD11c+ dendritic cells are effective initiators of CNS autoimmune disease

Dendritic cells (DC) play a crucial role in regulating T cell activation. Due to their capacity to shape the immune response, tolerogenic DC have been used to treat autoimmune diseases. In this study we examined whether 1,25 dihydroxyvitamin D3 conditioned bone marrow derived DC (VitD-BMDC) were abl...

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Detalles Bibliográficos

Principais autores:	Dario eBesusso, Louise eSaul, Richard eO'Connor, Mel eLeech, Andrew eMacDonald, Stephen M Anderton, Richard eMellanby
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2015-11-01
Series:	Frontiers in Immunology
Assuntos:	Multiple Sclerosis Vitamin D dendritic cell T cell Experimental autoimmune encephalomyelitis
Acceso en liña:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00575/full
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