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GluA2 is rapidly edited at the Q/R site during neural differentiation in vitro

The majority of AMPA receptors in the adult brain contain GluA2 subunits, which can be edited at the Q/R site, changing a glutamine to an arginine within the ion pore. Q/R editing renders AMPARs virtually Ca2+-impermeable, which is important for normal AMPA receptor function. Thus, all GluA2 subunit...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Svenja ePachernegg, Yvonne eMünster, Elke eMuth-Koehne, Gloria eFuhrmann, Michael eHollmann
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2015-03-01
Rangatū:Frontiers in Cellular Neuroscience
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00069/full
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