Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies

Melanoma is an aggressive skin cancer with a high rate of metastasis to other organs. Recent studies specified the overexpression of V-domain Ig suppressor of T-cell activation (VISTA) and Aryl Hydrocarbon Receptor (AHR) in melanoma. Metformin shows anti-tumor activities in several cancer types. How...

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Главные авторы:	Fawaz E. Alanazi, Homood M. As Sobeai, Khalid Alhazzani, Abdullah Al-Dhfyan, Musaad A Alshammari, Moureq Alotaibi, Khaled Al-hosaini, Hesham M. Korashy, Ali Alhoshani
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Springer 2022-02-01
Серии:	Saudi Pharmaceutical Journal
Предметы:	VISTA AHR CYP1A1 IDO1 Metformin CHL-1
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S1319016421002632
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