Cocktail of genetically diverse lytic phages reduces uropathogenic Escherichia coli colonization in mouse urinary tract

Abstract Urinary tract infections (UTIs) caused by uropathogenic Escherichia coli (UPEC) are one of the most common bacterial infections in humans. The rise of multidrug-resistant UPEC strains increases the urgent need for alternative treatment. Two diverse lytic bacteriophages (phages), SR02 and SR...

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Principais autores:	Panupon Mongkolkarvin, Chutikarn Sukjoi, Watcharapol Suyapoh, Songphon Buddhasiri, Ifeoluwa Emmanuel Ilugbusi, Poochit Nonejuie, Michael Harrison Hsieh, Vorrapon Chaikeeratisak, Parameth Thiennimitr
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2026-02-01
Serija:	Scientific Reports
Teme:	Uropathogenic Escherichia coli (UPEC) Urinary tract infection (UTI) Bacteriophage (phage) therapy Multidrug-resistant (MDR) UPEC Phage cocktail Mouse model for acute UTI
Online dostop:	https://doi.org/10.1038/s41598-026-39877-7
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