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Structural basis of human γTuRC closure during CM1-activated microtubule nucleation

Abstract Microtubule nucleation by the γ-tubulin ring complex (γTuRC) is spatiotemporally regulated and in higher eukaryotes is thought to involve a transition from an inactive open to an active closed conformation that matches the microtubule geometry. However, γTuRC activators only promote a parti...

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Bibliografiska uppgifter
Huvudupphov: Marina Serna, Cláudia Brito, Silvia Speroni, Fabian Zimmermann, Andrés Lopez-Perrote, Maria Gili, Cristina Lacasa, Jens Lüders, Thomas Surrey, Oscar Llorca
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2026-03-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-026-70773-w
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