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PfSRPK1 Regulates Asexual Blood Stage Schizogony and Is Essential for Male Gamete Formation

ABSTRACT Serine/arginine-rich protein kinases (SRPKs) are cell cycle-regulated serine/threonine protein kinases and are important regulators of splicing factors. In this study, we functionally characterize SRPK1 of the human malaria parasite Plasmodium falciparum. P. falciparum SRPK1 (PfSRPK1) was e...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sudhir Kumar, Vinay K. Baranwal, Amanda S. Leeb, Meseret T. Haile, Kenza M. Z. Oualim, Nina Hertoghs, Ashley M. Vaughan, Stefan H. I. Kappe
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2022-10-01
Schriftenreihe:Microbiology Spectrum
Schlagworte:
SRPK1
gametocyte
exflagellation
mosquito
transmission
RNA-seq
Online-Zugang:https://journals.asm.org/doi/10.1128/spectrum.02141-22
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