Phospholipase C signaling activated by parathyroid hormone mediates the rapid osteoclastogenesis in the fracture healing of orchiectomized mice

Abstract Background The age-related osteoporosis is an increasing risk severely threatening the live quality of aged people. Human parathyroid hormone (hPTH) is applied to the therapy of osteoporosis successfully, however, the mechanism, especially the signaling pathway activated in the healing frac...

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Κύριοι συγγραφείς:	Wei Li, Liang Yuan, Guojun Tong, Youhua He, Yue Meng, Song Hao, Jianting Chen, Jun Guo, Richard Bringhurst, Dehong Yang
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2018-08-01
Σειρά:	BMC Musculoskeletal Disorders
Θέματα:	Parathyroid hormone Fracture healing Phopholipase C Osteoporosis Osteoclastogenesis
Διαθέσιμο Online:	http://link.springer.com/article/10.1186/s12891-018-2231-3
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