Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen- γC- terminal fragments.

<h4>Objectives</h4>We previously reported microvascular leakage resulting from fibrinogen-γ chain C-terminal products (γC) occurred via a RhoA-dependent mechanism. The objective of this study was to further elucidate the signaling mechanism by which γC induces endothelial hyperpermeability. Since it...

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Principais autores:	Xiaohua Guo, Rebecca A Eitnier, Richard S Beard, Jamie E Meegan, Xiaoyuan Yang, Alexandra M Aponte, Fang Wang, Peter R Nelson, Mack H Wu
Format:	Artigo
Jezik:	Inglês
Izdano:	Public Library of Science (PLoS) 2020-01-01
Serija:	PLoS ONE
Online dostop:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0231739&type=printable
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