Influence of Hypoxia on the Epithelial-Pathogen Interactions in the Lung: Implications for Respiratory Disease

Under normal physiological conditions, the lung remains an oxygen rich environment. However, prominent regions of hypoxia are a common feature of infected and inflamed tissues and many chronic inflammatory respiratory diseases are associated with mucosal and systemic hypoxia. The airway epithelium r...

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Hlavní autoři:	Lee K. Page, Karl J. Staples, C. Mirella Spalluto, Alastair Watson, Tom M. A. Wilkinson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-03-01
Edice:	Frontiers in Immunology
Témata:	epithelial cells hypoxia hypoxia-inducible factor (HIF)-1 host-pathogen interactions innate immunity respiratory disease
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.653969/full
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