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A Comparison of Randomizing Either One Eye or Both Eyes in Clinical Trials for Stargardt Disease Type 1

Objective: Designing a clinical trial for rare diseases such as Stargardt disease type 1 is challenging due to the limited patient population. In traditional clinical trial designs for inherited retinal diseases, often only 1 eye of each patient is used as the treated eye or the sham, disregarding h...

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Principais autores: Jeroen A.A.H. Pas, MD, Patty P.A. Dhooge, MD, PhD, Catherina H.Z. Li, MD, Rob W.J. Collin, PhD, Carel B. Hoyng, MD, PhD, Joanna IntHout, PhD
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-02-01
coleção:Ophthalmology Science
Assuntos:
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666914525003197
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