The brain structure, inflammatory, and genetic mechanisms mediate the association between physical frailty and depression

Abstract Cross-sectional studies have demonstrated strong associations between physical frailty and depression. However, the evidence from prospective studies is limited. Here, we analyze data of 352,277 participants from UK Biobank with 12.25-year follow-up. Compared with non-frail individuals, pre...

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Autors principals:	Rongtao Jiang, Stephanie Noble, Matthew Rosenblatt, Wei Dai, Jean Ye, Shu Liu, Shile Qi, Vince D. Calhoun, Jing Sui, Dustin Scheinost
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-05-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-024-48827-8
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