Clodronate Treatment Prevents Vaginal Hypersensitivity in a Mouse Model of Vestibulodynia

IntroductionImproved understanding of vestibulodynia pathophysiology is required to develop appropriately targeted treatments. Established features include vulvovaginal hyperinnervation, increased nociceptive signalling and hypersensitivity. Emerging evidence indicates macrophage-neuron signalling c...

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Hlavní autoři:	Joel Castro, Andrea M. Harrington, Fariba Chegini, Dusan Matusica, Nick J. Spencer, Stuart M. Brierley, Rainer V. Haberberger, Christine M. Barry
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2022-01-01
Edice:	Frontiers in Cellular and Infection Microbiology
Témata:	vulvodynia vestibulodynia macrophage visceromotor reflex nociception clodronate peripheral nociceptor
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcimb.2021.784972/full
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