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Testing bidirectional associations of major depressive disorder with medical conditions: two-sample Mendelian randomization study

Abstract Depression is associated with increased risk for a variety of medical conditions. However, the extent to which these associations reflect a causal impact of depression on medical conditions, or vice-versa, remains unresolved. We tested bidirectional causal relationships between major depres...

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Detalhes bibliográficos
Principais autores: Yu Fang, Srijan Sen, Gita A. Pathak, Margit Burmeister, Leah S. Richmond-Rakerd
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2026-04-01
Colecção:npj Mental Health Research
Acesso em linha:https://doi.org/10.1038/s44184-026-00204-7
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