LOXL2-dependent deacetylation of aldolase A induces metabolic reprogramming and tumor progression

Lysyl-oxidase like-2 (LOXL2) regulates extracellular matrix remodeling and promotes tumor invasion and metastasis. Altered metabolism is a core hallmark of cancer, however, it remains unclear whether and how LOXL2 contributes to tumor metabolism. Here, we found that LOXL2 and its catalytically inact...

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Autori principali:	Ji-Wei Jiao, Xiu-Hui Zhan, Juan-Juan Wang, Li-Xia He, Zhen-Chang Guo, Xiu-E Xu, Lian-Di Liao, Xin Huang, Bing Wen, Yi-Wei Xu, Hai Hu, Gera Neufeld, Zhi-Jie Chang, Kai Zhang, Li-Yan Xu, En-Min Li
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2022-11-01
Serie:	Redox Biology
Soggetti:	Lysyl oxidase-like 2 Aldolase Glycolysis Deacetylation Tumorigenesis
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2213231722002683
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