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Germline mutational landscape in a large cohort of Indian breast cancer

Abstract Breast cancer has emerged as the leading malignancy among Indian women, with a notable subset of cases linked to inherited genetic predisposition. Germline testing is a vital tool for identifying individuals at elevated risk, guiding targeted therapies such as PARP inhibitors, and informing...

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Uloženo v:
Hlavní autoři: John Peter, Bani Jolly, Rajdeep Raha, Jayalakshmi Jothi, Avrajit Chakraborty, Swaminathan Ganapathi Raman, Selvi Radhakrishnan, Sridhar Sivasubbu, Vinod Scaria, Sundarasamy Mahalingam
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-12-01
Edice:BMC Cancer
Témata:
Breast Cancer, Genomics, Whole Exome Sequencing, Germline Testing
On-line přístup:https://doi.org/10.1186/s12885-025-15360-w
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