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Molecular architecture of heterochromatin at the nuclear periphery of primary human cells

Abstract In eukaryotes, meters of DNA are packaged into micrometer scale nuclei. Nucleosomes, as the major organizational unit, have been extensively studied in vitro, yet the elaborate 3D structure of chromatin inside cells and its distinct oligo-nucleosome arrangements remain poorly resolved. Here...

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Principais autores: Jan Philipp Kreysing, Sergio Cruz-León, Johannes Betz, Carlotta Penzo, Tomáš Majtner, Markus Schreiber, Beata Turoňová, Marina Lusic, Gerhard Hummer, Martin Beck
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2026-07-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-026-75087-5
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