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Biochemical mapping reveals a conserved heme transport mechanism via CcmCD in System I bacterial cytochrome c biogenesis

ABSTRACT Heme is a redox-active cofactor for essential processes across all domains of life. Heme’s redox capabilities are responsible for its biological significance but also make it highly cytotoxic, requiring tight intracellular regulation. Thus, the mechanisms of heme trafficking are still not w...

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Библиографические подробности
Главные авторы: Alicia N. Kreiman, Sarah E. Garner, Susan C. Carroll, Molly C. Sutherland
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2025-05-01
Серии:mBio
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Online-ссылка:https://journals.asm.org/doi/10.1128/mbio.03515-24
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