Controversial causal association between IGF family members and osteoporosis: a Mendelian randomization study between UK and FinnGen biobanks

ObjectivesOsteoporosis, a prevalent skeletal disorder characterized by reduced bone strength, is closely linked to the IGF system, crucial for skeletal metabolism. However, the precise nature of this relationship remains elusive. In this study, we employed Mendelian randomization (MR) to unravel the...

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Autors principals:	Jie Tang, Chanjuan Zhao, Sha Lin, Xing Li, Binlu Zhu, Yifei Li
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-01-01
Col·lecció:	Frontiers in Endocrinology
Matèries:	osteoporosis IGF-1 IGF family developmental disorders Mendelian randomization
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1332803/full
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