An Automated Imaging-Based Screen for Genetic Modulators of ER Organisation in Cultured Human Cells

Hereditary spastic paraplegias (HSPs) are a heterogeneous group of mono-genetic inherited neurological disorders, whose primary manifestation is the disruption of the pyramidal system, observed as a progressive impaired gait and leg spasticity in patients. Despite the large list of genes linked to t...

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Bibliografski detalji

Glavni autori:	M. Elena Garcia-Pardo, Jeremy C. Simpson, Niamh C. O’Sullivan
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-03-01
Serija:	Cells
Teme:	endoplasmic reticulum high-content imaging automated image analysis siRNA screen human cells
Online pristup:	https://www.mdpi.com/2073-4409/13/7/577
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