Biocatalytic structural diversification of saponins in Zygophyllum decumbens: HR-LC-ESI-TOF-MS/MS profiling and bioactivity modulation

Abstract Background Zygophyllum decumbens has been traditionally used in the treatment of gout, fungal infections, diabetes, and rheumatism. These therapeutic effects are primarily attributed to its triterpenoid saponins (TS). The present study explores the biocatalytic transformation of TS to exami...

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Principais autores:	Nagwan M. Gabr, Soad M. Abd-ElKhalik, Jaky T. Zaki, Lina J. M. Abdel-Hafez, Alaadin E. El-Haddad
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-04-01
coleção:	BMC Complementary Medicine and Therapies
Assuntos:	Zygophyllum decumbens Triterpenoid saponins Biocatalysis Antioxidant Antifungal Cytotoxicity
Acesso em linha:	https://doi.org/10.1186/s12906-026-05377-4
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