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The roles and acting mechanism of Caenorhabditis elegans DNase II genes in apoptotic dna degradation and development.

DNase II enzymes are acidic endonucleases that have been implicated in mediating apoptotic DNA degradation, a critical cell death execution event. C. elegans genome contains three DNase II homologues, NUC-1, CRN-6, and CRN-7, but their expression patterns, acting sites, and roles in apoptotic DNA de...

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Principais autores: Huey-Jen Lai, Szecheng J Lo, Eriko Kage-Nakadai, Shohei Mitani, Ding Xue
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2009-10-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC2752799?pdf=render
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