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Modeling the catarrhal stage of Bordetella pertussis upper respiratory tract infections in mice

Pertussis (whooping cough) is a highly transmissible human respiratory disease caused by Bordetella pertussis, a human-restricted pathogen. Animal models generally involve pneumonic infections induced by depositing large numbers of bacteria in the lungs of mice. These models have informed us about t...

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Principais autores: Illiassou H. Soumana, Kalyan K. Dewan, Bodo Linz, Israel Rivera, Longhuan Ma, Laura K. Howard, Amanda D. Caulfield, Colleen J. Sedney, Uriel Blas-Machado, Peter Sebo, Eric T. Harvill
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2022-05-01
Serier:Disease Models & Mechanisms
Fag:
bordetella pertussis
catarrhal stage
shedding
tlr4 receptor
mouse
Online adgang:http://dmm.biologists.org/content/15/5/dmm049266
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