Two-step screening method to identify α-synuclein aggregation inhibitors for Parkinson’s disease

Abstract Parkinson’s disease is a neurodegenerative disease characterized by the formation of neuronal inclusions of α-synuclein in patient brains. As the disease progresses, toxic α-synuclein aggregates transmit throughout the nervous system. No effective disease-modifying therapy has been establis...

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מידע ביבליוגרפי

Principais autores:	Makoto Hideshima, Yasuyoshi Kimura, César Aguirre, Keita Kakuda, Toshihide Takeuchi, Chi-Jing Choong, Junko Doi, Kei Nabekura, Keiichi Yamaguchi, Kichitaro Nakajima, Kousuke Baba, Seiichi Nagano, Yuji Goto, Yoshitaka Nagai, Hideki Mochizuki, Kensuke Ikenaka
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2022-01-01
סדרה:	Scientific Reports
גישה מקוונת:	https://doi.org/10.1038/s41598-021-04131-9
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!